Protocols (Rx)Dr. Horowitz: It is necessary to go after all the various forms of borrelia at the same time:
Lyme disease protocol for the chronically ill patients CPN protocol (chlamydia pneumonia)
The following MUST be taken in the combination suggested for at least 6 months (1 to 3 years duration may be necessary) in order to ensure successful treatment: 1. Amoxicillin and an amino acid NAC (N-acetyl cysteine)
2. Doxycycline
3. Azithromycin (Zithromax)
Rifampin
4. Flagyl (Metronidazole)
Nitrofurantoin (Macrobid or Macrodantin)
5. Isnoniazid (INH)
6. It is important to take an antifungal medication such as Diflucan (Fluconazole) – Suggested adult dosage: 100 mg weekly or bi-weekly 7. Take probiotics such as acidophilus to control yeast and restore friendly bacteria (at least 3 billion cells a day) http://web.archive.org/web/20070515234306/ http://www.umm.edu/altmed/articles/lactobacillus-000310.htm 8. Multivitamins are also recommended (refer to link) http://web.archive.org/web/20070515234306/ http://www.cpnhelp.org/allsupplementspdf http://www.cpnhelp.org/allsupplementspdf 9. Anti-inflammatory agents such as Celebrex (suggested adult dosage: 200 mg once per day) may help control inflammation and pain during treatment Protocols (Alt)
Dr. Zhang's protocol
-from Hepapro.com How to take herb.pdf
-from Latitudes.org Anyone tried Dr Zhang's protocal? Note: First you need to understand that Zhang's protocol is not Traditional Chinese Medicine. What he has done is make pharmaceutical grade products from herbs. |
Theory and dataComplement split products c3a and c4a in chronic lyme disease.
I had extremely elevated C4a when I got tested years ago, according to this article, the only possibility is Spirochete or Lyme disease. However, according to Dr. Shoemaker, elevated C4a is also one sign of mold illness. Chlamydia Pneumonia Explanation:
What is Chlamydia pneumonia? Chlamydia Pneumonia (Cpn) is a tiny, intracellular, parasitic bacteria that invades the body’s cells and steals the cell’s energy making the cell lose all functionality. It is a very difficult bacteria to culture and therefore can go undetected for a long period of time. This infection is the BIGGEST cause of Cpn related diseases including Morgellons symptoms. Once this infection is cleared up, Morgellons symptoms dissipate. How do you contract Cpn? Cpn has 3 life form stages that can adapt if they are threatened:
It starts as a respiratory tract infection such as bronchitis, pneumonia, sinusitis, or laryngitis. Coming into contact with an infected person’s contaminated droplets through coughing or sneezing transmits it. This transmits the EB forms from person to person. Once the EB forms enter the body, they can invade ANY cell (e.g., blood, brain, or immune cells). The EB forms take over the cells that they invade making the cell stop functioning…i.e., it can no longer do what it is supposed to do such as fight off infection. http://www.cpnhelp.org/cpnbook http://web.archive.org/web/20070515234306/http://www.cpnhelp.org/cpnbook What is Chamydia pneumonia, CPN, and what does it have to do with Lyme disease?
http://lymemd.blogspot.com/2008/05/what-is-chamydia-pneumonia-cpn-and-what.html The controversial notion that Lyme causes "everything."
There are a group of physicians who are doing parallel research. They believe that Chlamydia pneumonia, or CPN, is the cause of everything.
These two infections intersect at the word L-form. Both exist as intracellular organisms called L-forms. CPN has a 3 phase life cycle which is somewhat reminiscent of Lyme. CPN is very hard to kill. Studies show that it takes months or years of combination antibiotic therapy to eliminate this organism. CPN is ubiquitous. It is common respiratory pathogen, not to be confused with its cousin Chlamydia trachomatis, a sexually transmitted pathogen. Most of the research on CPN has been done at The Vanderbilt School of Medicine. The chief expert in this area is Dr. Charles Stratton. Dr. David Weldon, a researcher and clinician in England has provided compelling evidence showing a link between CPN and MS. He reports anecdotal evidence of his success in treating MS patients. More startling is the work of Dr. Martz, a victim of ALS, Lou Gehrig's disease. He was shown to be infected with Lyme. Intravenous treatment with Rocephin caused a remission of his otherwise fatal illness. He has treated both ALS and MS patients for Lyme and met with some success. However, his findings have not yet been published. Protocols for treating CPN include Amoxicillin, Docycyline, Zithromax and Flagyl. Interesting. These are all Lyme drugs. Dr. Stratton has also recommended Rifampin, which at times is very effective as a Lyme therapy. He also recommends INH, an anti-Tuberculosis drug, which most physicians avoid because the risk of liver toxicity is substantial. Many patients evaluated for Lyme have high antibody titers to CPN. Since it is an intracellular germ it is difficult, like Borrelia, to prove it is causing active infection. However laboratory experiments attest to its hardiness and its uncanny ability to defeat both the immune system as well as antibiotics. These two areas of research and treatment have been separate from one another. Again the commonality is the idea of chronic L-form infection leading to a host of consequences. Patients with a high L-form burden may be more likely to have vitamin D dysfunction with reversal of normal levels, as described by Marshall. The importance of CPN may be that simultaneous infection with Borrelia makes treatment more challenging. It may help direct the choices of antibiotics as well as the likely duration of treatment. CPN is not a Lyme co-infection because it is not tick borne. It may ultimately be of much greater importance than the usual co-infections that are stressed by most "Lyme" doctors. Most "Lyme literate MDs" do not discus CPN. Doctors who specialize in CPN, there are not many of them at this time, seem to be unaware of Lyme literature. I believe the integration of these two areas will eventually lead to newer thinking and treatment for what is becoming rather than just Lyme disease, but the Lyme complex syndrome. Evaluation of in-vitro antibiotic susceptibility of different morphological forms of Borrelia burgdorferi
Results: Doxycycline reduced spirochetal structures ~90% but increased the number of round body forms about twofold. Amoxicillin reduced spirochetal forms by ~85%–90% and round body forms by ~68%, while treatment with metronidazole led to reduction of spirochetal structures by ~90% and round body forms by ~80%. Tigecycline and tinidazole treatment reduced both spirochetal and round body forms by ~80%–90%. When quantitative effects on biofilm-like colonies were evaluated, the five antibiotics reduced formation of these colonies by only 30%–55%. In terms of qualitative effects, only tinidazole reduced viable organisms by ~90%. Following treatment with the other antibiotics, viable organisms were detected in 70%–85% of the biofilm-like colonies. Conclusion: Antibiotics have varying effects on the different morphological forms of B. burgdorferi. Persistence of viable organisms in round body forms and biofilm-like colonies may explain treatment failure and persistent symptoms following antibiotic therapy of Lyme disease. Chronic Lyme Disease and Co-infections: Differential Diagnosis
Open Neurol J. 2012; 6: 158–178. fulltext Walter Berghoff* |